Silva-Fisher lab
at Washington University School of Medicine
Our lab is driven to uncover how a unique class of molecules, long non-coding RNAs (lncRNAs), shape the way cancer cells grow, survive, and respond to treatment. Although these RNAs do not code for proteins, they play powerful roles inside the cell, and we aim to understand exactly how they work.
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We focus on how lncRNAs interact with proteins and regulate essential processes like the cell cycle. By combining large-scale human genomic datasets with cutting-edge laboratory experiments, we connect patterns we see in patients to the molecular mechanisms driving cancer in cells.
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Our goal is to reveal how RNA directs cancer biology and to use these insights to identify new ways to detect disease earlier, monitor it more precisely, and ultimately develop better, more targeted treatments.
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Our goal is to find a cure for cancer and we need funding support for staff, students, and supplies, to do this.
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Thank you for your kindness, generosity, and love of RNA!