Silva-Fisher lab
at Washington University School of Medicine
Our lab explores how a hidden layer of biology, called long non-coding RNAs (lncRNAs), influences cancer.
Unlike most genes, lncRNAs don’t make proteins. For a long time, they were overlooked. We now know they play powerful roles in controlling how cells grow, survive, and respond to treatment. Our research aims to understand how these molecules work and why they matter in cancer.
We combine insights from patient data with hands-on laboratory experiments to connect what we see in tumors to what’s happening inside cancer cells. This helps us uncover the mechanisms that drive disease.
Our goal is simple but ambitious: to turn new knowledge about RNA into better ways to detect cancer earlier, track it more accurately, and develop more effective, targeted treatments for patients.
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Our goal is to find a cure for cancer and we need funding support for staff, students, and supplies, to do this.
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