The Silva-Fisher Lab
at Washington University in St. Louis
Our Mission is to ask and answer critical, questions in identifying why and how cancer metastasizes. We do this by conducting innovative and advanced research in a welcoming and supportive research environment.
Our Research focus is to study the basic mechanisms of regulatory RNAs including non-protein coding genes called long non-coding RNAs (lncRNAs) to target them and use them for new cancer treatments.
"Circle of Translational Science"
Our research begins by obtaining tumor samples (or available patient data), sequencing these samples with various methods of next generation sequencing technologies, identifying de-regulated long non-coding RNAs and their associated protein interactors, then using advanced technologies for their characterization, function, and mechanism, to lastly apply this information for creating novel lncRNA therapies.
Washington University in St. Louis
Department of Medicine
Division of Oncology
4950 Childrens Pl, St.Louis, Mo, 63110