Conferences/Published Abstracts

fig1 sydney poster.png

Identification of long non-coding RNAs as biomarkers for multiple myeloma progression

April 2021

Sydney Anderson, Lijun Yao, Prasanth Thunuguntla, Julia Wang, Li Ding, and Jessica Silva-Fisher

2021 NHGRI Research Training and Career Development Annual Meeting, Virtual Meeting UCLA David Geffen School of Medicine

Fig1 jess rna society abstract.png

Identification and characterization of Multiple Myeloma associated long non-coding RNAs (MMals) using single cell sequencing and their potential roles in multiple myeloma drug resistance

May 2021

Sydney Anderson, Prasanth Thunuguntla, Lijun Yao, Li Ding, and Jessica Silva-Fisher

RNA Society 2021


Relevant Published Work

Includes previous work

Voices on Diversity: Overcoming Barriers to Pursue a Career in Science


Voices on Diversity: Multiple Paths to Becoming a Scientist


Silva-Fisher J, Nervo LM, Addo T, Guerra A, Walker M, Guerrier S, McGill L, Brooks D, Joseph J, Johnson J, Ayombil F, Odinammadu K Mol Cell 2020 Dec 3;80(5):752-757

Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression.


Silva-Fisher, J.M., Dang, H.X., White, N.M. et al. Nat Commun 11, 2156 (2020).

Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function.


Cabanski CR, White NM, Dang HX, Silva-Fisher JM, Rauck CE, Cicka D, Maher CA: RNA Biol 2015, 12(6):628-
642.4615893. Pubmed Central PMID: 5864709

Transcriptome sequencingreveals altered long intergenic non-coding RNAs in lung cancer.


White NM, Cabanski CR, Silva-Fisher JM, Dang HX, Govindan R, Maher CA: Genome Biol 2014, 15(8):429.4156652.
Pubmed Central PMID: 25116943

Long non-coding RNAs and Cancer


Silva Jessica M and Smith David I. (2011) Long non-coding RNAs and Cancer in Kevin V. Morris (Eds), Long
Non-coding RNAs: Regulation of Gene Expression and Drivers of Natural Selection, (Chapter 9) The
Scripps Research Institute, La Jolla, California, Caister Academic Press

LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation.


Silva JM, Boczek NJ, Berres MW, Ma X, Smith DI: RNA Biol 2011, 8(3):496-505. Pubmed Central PMID: 21532345

Identification of long stress-induced noncoding transcripts that have altered expression in cancer.


Silva JM, Perez DS, Pritchett JR, Halling ML, Tang H, Smith DI: Genomics 2010, 95(6):355-362. Pubmed
Central PMID: 20214974

Akt-Induced Tamoxifen Resistance Is Associated With Altered FKHR Regulation


Silva J, Cavazos DA, Donzis E, Friedrichs WE, Marciniak R, deGraffenried LA
Cancer Invest 2007;25(7):569-73

Inhibition of mTOR Activity Restores Tamoxifen Response in Breast Cancer Cells With Aberrant Akt Activity


deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M
Clin Cancer Res 2004 Dec 1;10(23):8059-67

NF-Kappa B Inhibition Markedly Enhances Sensitivity of Resistant Breast Cancer Tumor Cells to Tamoxifen


deGraffenried LA, Chandrasekar B, Friedrichs WE, Donzis E, Silva J, Hidalgo M, Freeman JW, Weiss GR
Ann Oncol 2004 Jun;15(6):885-90

Eicosapentaenoic Acid Restores Tamoxifen Sensitivity in Breast Cancer Cells With High Akt Activity


deGraffenried LA, Friedrichs WE, Fulcher L, Fernandes G, Silva JM, Peralba JM, Hidalgo M
Ann Oncol 2003 Jul;14(7):1051-6