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Conferences/Published Abstracts

Long non-coding RNA LINC00355 expression and treatment using antisense oligonucleotides in Estrogen Receptor positive late-stage relapse breast cancer

December 2022

DeAnna Wells, Kyla Gelev, Savannah Gonzales, Prasanth K. Thunuguntla, Reyka Jayasinghe, Jieya Shao, Li Ding, Cynthia Ma, Jessica Silva-Fisher

San Antonio Breast Cancer Symposium 2022

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LINC00355-Menin interaction promotes proliferation in late-stage relapse breast cancer

July 2022

Kyla Z. Gelev, Abdallah M. Eteleeb, Prasanth K. Thunuguntla, Cynthia Y. Tang, Emily B. Rozycki, Alexander Miller, Jonathan T. Lei, Ha X. Dang, Nicole M. White, Jorge S. Reis-Filho, Elaine R. Mardis, Matthew J. Ellis, Christopher A. Maher and Jessica Silva-Fisher

RNA 2022 Conference


Identifying LINC00355 lncRNA as a therapeutic target in Late-Stage Relapse Breast Cancer

May 2022

Kyla Z. Gelev, Prasanth K. Thungunutla,  Abdallah M. Eteleeb, Mathew J. Ellis, Christopher A. Maher, and Jessica M. Silva-Fisher

2022 NHGRI Research Training and Career Development Annual Meeting

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Identification of long non-coding RNAs as biomarkers for multiple myeloma progression

April 2021

Sydney Anderson, Lijun Yao, Prasanth Thunuguntla, Julia Wang, Li Ding, and Jessica Silva-Fisher

2021 NHGRI Research Training and Career Development Annual Meeting, Virtual Meeting UCLA David Geffen School of Medicine

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Identification and characterization of Multiple Myeloma associated long non-coding RNAs (MMals) using single cell sequencing and their potential roles in multiple myeloma drug resistance

May 2021

Sydney Anderson, Prasanth Thunuguntla, Lijun Yao, Li Ding, and Jessica Silva-Fisher

RNA Society 2021

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Publications: Research

Relevant Lab Publications

Includes previous work

LINC00355 regulates p27KIP expression by binding to MENIN to induce proliferation in late-stage relapse breast cancer.


Eteleeb, A.M., Thunuguntla, P.K., Gelev, K.Z. et al. npj Breast Cancer 8, 49 (2022).

Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression.


Silva-Fisher, J.M., Dang, H.X., White, N.M. et al. Nat Commun 11, 2156 (2020).

Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function.


Cabanski CR, White NM, Dang HX, Silva-Fisher JM, Rauck CE, Cicka D, Maher CA: RNA Biol 2015, 12(6):628-
642.4615893. Pubmed Central PMID: 5864709

Transcriptome sequencingreveals altered long intergenic non-coding RNAs in lung cancer.


White NM, Cabanski CR, Silva-Fisher JM, Dang HX, Govindan R, Maher CA: Genome Biol 2014, 15(8):429.4156652.
Pubmed Central PMID: 25116943

Long non-coding RNAs and Cancer


Silva Jessica M and Smith David I. (2011) Long non-coding RNAs and Cancer in Kevin V. Morris (Eds), Long
Non-coding RNAs: Regulation of Gene Expression and Drivers of Natural Selection, (Chapter 9) The
Scripps Research Institute, La Jolla, California, Caister Academic Press

LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation.


Silva JM, Boczek NJ, Berres MW, Ma X, Smith DI: RNA Biol 2011, 8(3):496-505. Pubmed Central PMID: 21532345

Identification of long stress-induced noncoding transcripts that have altered expression in cancer.


Silva JM, Perez DS, Pritchett JR, Halling ML, Tang H, Smith DI: Genomics 2010, 95(6):355-362. Pubmed
Central PMID: 20214974

Akt-Induced Tamoxifen Resistance Is Associated With Altered FKHR Regulation


Silva J, Cavazos DA, Donzis E, Friedrichs WE, Marciniak R, deGraffenried LA
Cancer Invest 2007;25(7):569-73

Inhibition of mTOR Activity Restores Tamoxifen Response in Breast Cancer Cells With Aberrant Akt Activity


deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M
Clin Cancer Res 2004 Dec 1;10(23):8059-67

NF-Kappa B Inhibition Markedly Enhances Sensitivity of Resistant Breast Cancer Tumor Cells to Tamoxifen


deGraffenried LA, Chandrasekar B, Friedrichs WE, Donzis E, Silva J, Hidalgo M, Freeman JW, Weiss GR
Ann Oncol 2004 Jun;15(6):885-90

Eicosapentaenoic Acid Restores Tamoxifen Sensitivity in Breast Cancer Cells With High Akt Activity


deGraffenried LA, Friedrichs WE, Fulcher L, Fernandes G, Silva JM, Peralba JM, Hidalgo M
Ann Oncol 2003 Jul;14(7):1051-6

Publications: Publications

Diversity, Equity, and Inclusion Publications

Voices on diversity: Support systems that work.


Nervo LM, Ayombil F, Addo T, Guerra A, Walker M, McGill L, Joseph J, Silva-Fisher J
Mol Cell. 2021 Mar 4;81(5):885-888. doi: 10.1016/j.molcel.2021.01.027. PubMed PMID: 33667376

Voices on diversity: confronting racial bias.


Guerra A, Nervo LM, Addo T, Walker M, McGill L, Joseph J, Johnson J, Silva-Fisher J.
Mol Cell. 2021 Feb 18;81(4):639-641. doi: 10.1016/j.molcel.2021.01.026. PubMed PMID: 33606970.

Voices on diversity: recruiting underrepresented scientists.


Joseph J, Johnson J, Ayombil F, Silva-Fisher J, Guerrier S, Nervo LM, Addo T, McGill L, Brooks D. 

Mol Cell. 2021 Feb 4;81(3):414-417. doi: 10.1016/j.molcel.2021.01.017. PubMed PMID: 33545055.

Voices on Diversity: Creating a Sense of Belonging


McGill L, Brooks D, Joseph J, Silva-Fisher J, Guerrier S, Addo T, Guerra A, Walker M, Johnson J, Ayombil F, Odinammadu K
Mol Cell. 2021 Jan 21;81(2):213-217. doi: 10.1016/j.molcel.2020.12.045. PubMed PMID: 33482088

Voices on diversity: Combating Racial Inequality to Increase Diversity


Silva-Fisher J, Guerrier S, Nervo LM, Guerra A, McGill L, Brooks D, Joseph J, Walker M, Ayombil F, Odinammadu K

Mol Cell. 2021 Jan 7;81(1):1-5. doi: 10.1016/j.molcel.2020.12.022. PubMed PMID: 33417852.

Voices on Diversity: Overcoming Barriers to Pursue a Career in Science


Voices on Diversity: Multiple Paths to Becoming a Scientist


Silva-Fisher J, Nervo LM, Addo T, Guerra A, Walker M, Guerrier S, McGill L, Brooks D, Joseph J, Johnson J, Ayombil F, Odinammadu K Mol Cell 2020 Dec 3;80(5):752-757

Publications: Publications
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